Preservation of the Caerphilly Prospective Study (CaPS)

Data-sharing agreement from NHS England Data Uses Register. Evidence status: source reported.

Organisation: UNIVERSITY OF BRISTOL
Published: 2026-09-25
Source reference: DARS-NIC-148336-V4SL1-v6.2
Jurisdiction: England
Licence: Open Government Licence v3.0, subject to NHS England terms and exclusions

Register reference: DARS-NIC-148336-V4SL1-v6.2
Applicant type: Academic
Data controllers: UNIVERSITY OF BRISTOL
Agreement period: 2026-09-25 to 2028-10-31
For commercial purposes (as marked in the register): No
Release files listed by NHS England: 0

Data approved

Cancer Registration Data
Civil Registrations of Death
Demographics
MRIS - Cause of Death Report
MRIS - Cohort Event Notification Report

Objective, as published

The University of Bristol requires access to NHS England Data for the purpose of the following research programme: The Caerphilly Prospective Study (CaPS) The following is a summary of the aims of the research programme provided by the University of Bristol: “The Caerphilly Prospective Study (CaPS) was initially set up in the late 1970s. The initial objective of CaPS was to establish the relation between specific biochemical and physiological variables and the prevalence and incidence of ischaemic heart disease (IHD). Over the years the number of outcome measures has been enlarged with a specific focus on cognitive impairment, dementia and ageing traits in the later years. The overall aim of CaPS is to enhance the understanding of life course influences on the causes of chronic disease and physiological traits by examining lifestyle, genetic and other exposures at various times in the life course and determine whether these predict a wide range of different outcomes.” The University of Bristol wish to collect outcome Data from NHS England to add to the variables collected from the cohort since the 1970s, with the intention of following the whole cohort until their death. This is unusual in most studies and scientifically valuable. The University of Bristol therefore wish to make this linked Data available to other researchers across the University; and also to make CaPS data linked to information derived from NHS England Data more widely available to other researchers, in or…

Expected benefits, as published

The types of benefit that may arise from the CaPS study are health related and may result in new methods of disease prevention or prediction. This may benefit the provision of health and/or adult social care by allowing disease modellers and health economists to predict future disease trends. CaPS study findings are in the public interest in terms of enhancing understanding of how to prevent disease. The use of the Data could: • lead to the identification or improvement of treatments or interventions • advance understanding of the need for, or effectiveness of, preventative health and care measures for particular populations • support knowledge creation or exploratory research (and the innovations and developments that might result from that exploratory work). It is hoped that through pub…

Benefits reported by the applicant

CaPS data has contributed to studies that look at a risk factor or trait over the life course by merging datasets that have data over different life stages e.g. childhood, young adulthood, middle age, older age etc. This has shown the interesting pattern as to how blood pressure changes over the life course. This highlights important ages where prevention strategies may have more impact on health. One impact of this sort of research has been the specific targeting of research funding by UK Research and Innovation, the National Institute for Health and Care Research, and the Global Alliance for Chronic Diseases on life course research and interventions targeting specific critical or sensitive time periods (see https://www.gacd.org/funding/current-call-for-applications/common-risk-factors).…

This is the applicant's own account; OpenHDI has not verified it.

Source: https://digital.nhs.uk/services/data-access-request-service-dars/data-uses-register. Captured 2026-11-05.

Limitations: Data-sharing agreement as published in NHS England's Data Uses Register. An agreement permits access; actual data releases are listed separately. Expected and yielded benefits are as reported by the applicant and have not been independently verified. Long text fields can be cut off in NHS England's spreadsheet export at Excel's 32,767-character cell limit.