Epidemiology and Prognosis in Acute Myocarditis

Data-sharing agreement from NHS England Data Uses Register. Evidence status: source reported.

Organisation: GUY'S AND ST THOMAS' NHS FOUNDATION TRUST
Published: 2026-09-01
Source reference: DARS-NIC-144568-D7G6V-v6.7
Jurisdiction: England
Licence: Open Government Licence v3.0, subject to NHS England terms and exclusions

Register reference: DARS-NIC-144568-D7G6V-v6.7
Applicant type: NHS Trust
Data controllers: GUY'S AND ST THOMAS' NHS FOUNDATION TRUST
Agreement period: 2026-09-01 to 2029-12-16
For commercial purposes (as marked in the register): No
Release files listed by NHS England: 0

Data approved

Civil Registrations of Death
Civil Registrations of Death - Secondary Care Cut
COVID-19 Hospitalization in England Surveillance System
COVID-19 SGSS First Positives (Second Generation Surveillance System)
HES:Civil Registration (Deaths) bridge
HES-ID to MPS-ID HES Admitted Patient Care
Hospital Episode Statistics Admitted Patient Care (HES APC)

Objective, as published

Guy’s and St Thomas’ NHS Foundation Trust requires access to NHS England data for the purpose of the following research project: Epidemiology and Prognosis in Acute Myocarditis. The following is a summary of the aims of the research project provided Guy’s and St Thomas’ NHS Foundation Trust. “Royal Brompton Hospital (a part of the Royal Brompton and Harefield Clinical Group clinical group within the Guy's and St Thomas' NHS Foundation Trust) aims to describe the longitudinal epidemiological trends of acute myocarditis and related conditions referring to pericarditis and cardiomyopathy to provide a contemporary, population-level assessment of the burden of disease and how this may have changed since 1997. National data is therefore required from 1997/98 to the latest available period to analyse changes and variation arising from medical, biological, geographical, and social factors. “Myocarditis means inflammation of the heart muscle and is known to predominantly affect young adults aged between 19- 35 years. It is usually related to a recent viral infection. Patients often present with severe, sudden-onset chest pain mimicking a heart attack, difficulty breathing due to weakened heart muscle, and/or palpitations due to electrical rhythm disturbances within the heart. However, myocarditis also affects infants and older adults where causative factors, and clinical outcomes are poorly characterised. In the long-term, up to one third of patients are at risk of developing heart f…

Expected benefits, as published

The findings of this research study are expected to contribute to evidence-based decision-making for policymakers, local decision-makers such as doctors, and patients to inform best practice to improve the care, treatment, and experience of health care users relevant to the subject matter of the study. The use of the data could: • help the system to better understand the health and care needs of populations. • lead to the identification or improvement of treatments or interventions, or health and care system design to improve health and care outcomes or experience. • advance understanding of regional and national trends in health and social care needs. • inform planning health services and programmes, for example to improve equity of access, experience, and outcomes. • inform decisions on…

Benefits reported by the applicant

Yielded benefits to date The data supplied under this agreement have generated demonstrable benefit for patients, clinicians and policymakers, both locally, nationally and internationally, across three areas: scientific output, influence on clinical practice and policy, and patient and public engagement. Scientific output and dissemination Early epidemiological analyses of myocarditis admissions and outcomes were presented by the Study Lead at the American Heart Association Annual Scientific Session in Philadelphia (November 2019) and published in Circulation (https://www.ahajournals.org/doi/10.1161/circ.140.suppl_1.11463). Further analyses formed part of the Study Lead's PhD, awarded by Imperial College London in October 2020. The national admission data have since underpinned a major in…

This is the applicant's own account; OpenHDI has not verified it.

Source: https://digital.nhs.uk/services/data-access-request-service-dars/data-uses-register. Captured 2026-11-05.

Limitations: Data-sharing agreement as published in NHS England's Data Uses Register. An agreement permits access; actual data releases are listed separately. Expected and yielded benefits are as reported by the applicant and have not been independently verified. Long text fields can be cut off in NHS England's spreadsheet export at Excel's 32,767-character cell limit.