UNIVERSITY OF SHEFFIELD: The data obtained from DARS (NHS digital) shall be processed solely for the CENTER-TBI registry work package (17).

Data-sharing agreement from NHS Digital registers of approved data releases, 2014–2019. Evidence status: source reported.

Organisation: University of Sheffield
Source reference: DARS-NIC-62448-Z8K5T-v0.9
Jurisdiction: England
Licence: Open Government Licence v3.0, subject to NHS England terms and exclusions

Register reference: DARS-NIC-62448-Z8K5T-v0.9
Agreement period: not published to no end date published
For commercial purposes (as marked in the register): Not stated
Release files listed by NHS England: 6

Data approved

Hospital Episode Statistics Admitted Patient Care
Hospital Episode Statistics Accident and Emergency
Hospital Episode Statistics Critical Care

Objective, as published

The data obtained from DARS (NHS digital) shall be processed solely for the CENTER-TBI registry work package (17). The CENTER-TBI study consists of 20 workpackages . The overall aims of the whole CENTER - TBI study are: - To improve characterization and classification of TBI in Europe, with inclusion of emerging technologies. - To identify the most effective clinical care and to provide high quality evidence in support of treatment recommendations and guidelines. In summary, the core study will be recruiting TBI patients across Europe to collect high-quality clinical and epidemiological data with repositories for neuro-imaging, DNA and serum from patients with TBI in order to improve TBI characterisation and identify the most effective TBI treatments, The CENTER-TBI core study will be making comparisons in treatments and interventions across 80 centres and 21 countries. This approach is called Comparative Effectiveness Research (CER). Therefore, data shall be collected from these European centres to enable CER analyses of differences in clinical care and management pathways in TBI. A total of 5400 TBI patients will be recruited from acute hospitals; the emergency department, in-patient wards and intensive care. Data and blood samples will be collected but in some cases a non-invasive scan of the brain (MRI scan) will be done. Patients will be followed up for up to 2 years. Patients with a clinical indication for CT scan who present to the hospital within 24 hours of TBI inju…

Expected benefits, as published

Previously, the introduction of the UK National Institute for Health and Care Excellence Guidelines for TBI management in 2003 was associated with a 12% reduction in TBI mortality. These guidelines were around improved access to imaging for early diagnosis of TBI as well as improved access to specialist neuroscience care for TBI. However, there have been no new therapies for TBI in the last 30 years. It is therefore reasonable to expect to realise similar benefits at the end of the CENTER-TBI project when the research team has achieved an improved understanding of the most complex disease in the most complex organ (TBI) and further identified new therapies through this comparative effectiveness research in addition to the current guidelines by NICE. A cascade of benefits will follow the d…

Source: https://webarchive.nationalarchives.gov.uk/ukgwa/2019/https://digital.nhs.uk/binaries/content/assets/legacy/excel/2/1/releaseregister20171201_20180228.xlsx. Captured 2026-10-30.

Limitations: Agreement as recorded in an NHS Digital register of approved data releases (2014–2019), retrieved from the UK Government Web Archive. That register lists releases made in its period and the agreement's purpose statement as it then stood; it gives no agreement dates, and the agreement may have changed since. Imported only where a paper quotes a reference no current register holds.