Imperial College London: To facilitate complete reporting of mortality for a randomised trial of an endovascular strategy versus open repair for patients with a clinical diagnosis of ruptured abdominal aor

Data-sharing agreement from NHS Digital registers of approved data releases, 2014–2019. Evidence status: source reported.

Organisation

Imperial College London

Source reference

DARS-NIC-287804-H1T1R-v1.3

Jurisdiction

England

Licence

Open Government Licence v3.0, subject to NHS England terms and exclusions

To facilitate complete reporting of mortality for a randomised trial of an endovascular strategy versus open repair for patients with a clinical diagnosis of ruptured abdominal aortic aneurysm (IMPROVE ISRCTN48334791), which is supported by the National Institute for Health Research. The primary outcome of this trial is 30-day mortality and secondary outcomes are 1 year and 3 year mortality and aneurysm-related mortality. The most recent data file was received for these patients in December 2015. To enable full patient follow up for a minimum of 3 years, data are needed for deaths through July

Register reference

DARS-NIC-287804-H1T1R-v1.3

Agreement period

not published to no end date published

For commercial purposes (as marked in the register)

Not stated

Release files listed by NHS England

11

Data approved

• MRIS - Cause of Death Report
• MRIS - Cohort Event Notification Report
• MRIS - Members and Postings Report

Objective, as published

To facilitate complete reporting of mortality for a randomised trial of an endovascular strategy versus open repair for patients with a clinical diagnosis of ruptured abdominal aortic aneurysm (IMPROVE ISRCTN48334791), which is supported by the National Institute for Health Research. The primary outcome of this trial is 30-day mortality and secondary outcomes are 1 year and 3 year mortality and aneurysm-related mortality. The most recent data file was received for these patients in December 2015. To enable full patient follow up for a minimum of 3 years, data are needed for deaths through July 2016 (last patient in the study will complete 3-year follow-up on 21st July 2016). The trial included critically ill patients often in great pain. Either patients or a relative/carer/welfare guardian on behalf of the patient have signed a consent form before aneurysm repair. After recovery patients provided fully informed consent for continued participation in the trial, which included consent to access “their data from NHS Information Centre and NHS Central Register NHS information”.

Expected benefits, as published

1. To enable discrimination between aneurysm-related and other causes of death in the mid-term, as well as full patient follow up for mortality, following endovascular or open repair of ruptured abdominal aortic aneurysm: 2015-2017. 2. To benefit all future patients admitted to hospital with a diagnosis of ruptured abdominal aortic aneurysm (from 2015) 3. To drive organizational changes, so that endovascular repair becomes available to all patients with ruptured abdominal aortic aneurysm (from 2015)

Source: https://webarchive.nationalarchives.gov.uk/ukgwa/2019/http://content.digital.nhs.uk/media/23861/Release-Register-December-16---February-17/xls/Release_Register__December_16_-_February_17.xlsx. Captured 2026-10-30.

Limitations: Agreement as recorded in an NHS Digital register of approved data releases (2014–2019), retrieved from the UK Government Web Archive. That register lists releases made in its period and the agreement's purpose statement as it then stood; it gives no agreement dates, and the agreement may have changed since. Imported only where a paper quotes a reference no current register holds.